Breakthrough

Breakthrough

Advances in neuro-immunology treat incurable brain disease

In Science, Chinese scientists published on the creation of a new model for a genetic brain disorder and tested a potential treatment which worked in both mice and humans.

Andreas Huysman's avatar
Andreas Huysman
Jul 24, 2025
∙ Paid

"All models are wrong", stated statistician George Box in a paper published in 1976; however, he follows up by saying, "the ability to devise simple but evocative models is the signature of the great scientist". A group of neuroscientists just published an incredible paper in which they developed a mouse model for a rare and debilitating neurological disease called CSF1R-associated microgliopathy (CAMP), or ALSP, which stands for adult-onset leukoencephalopathy with axonal spheroids and pigmented glia. Even more impressive, they discovered a method to halt the disease's progression.

User's avatar

Continue reading this post for free, courtesy of Samuel Hume.

Or purchase a paid subscription.
© 2026 Samuel Hume · Privacy ∙ Terms ∙ Collection notice
Start your SubstackGet the app
Substack is the home for great culture